Method Development and Validation of Metformin Hydrochloride in Tablet Dosage Form
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چکیده
منابع مشابه
Development and Validation of Uv Spectroscopic Method for the Determination of Metformin Hydrochloride in Tablet Dosage Form
A simple, economic, sensitive, precise and accurate UV spectrophotometric method was developed and validated for quantification of Metformin hydrochloride in bulk and in tablet dosage form. Adequate drug solubility and maximum assay sensitivity was found in 0.01N sodium hydroxide at 233nm. Calibration graph constructed at 233nm was linear in concentration range of 1-25μg/ml with correlation coe...
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A RP-HPLC method was developed for the estimation of Atomoxetine Hydrochloride in tablet formulation, which is novel to the market. Chromatographic separation of the drug was achieved on a ENABLE C-18 G, 5μm, column (250 × 4.6 mm) using a mobile phase, Methanol: Ammonium phosphate buffer pH-3 (80:20 V/V) at a flow rate of 1ml/min. The drug eluted was monitored at 227 nm. The retention time was ...
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A new simple, fast accurate and reproducible reverse phase high performance liquid chromatographic method has been developed and validated for simultaneous estimation of Metformin Hydrochloride and Glimepiride from tablet dosage form. The method was developed using Waters HPLC system on C18 column (Spherisorb ODS 2: 250mm x 4.6 μm) using a mixture of 25mM Phosphoric Acid pH 3.0 (with KOH) and A...
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Duloxetine hydrochloride is a potent dual reuptake inhibitor of serotonin and norepinephrine used to treat major depressive disorders. The present work describes a simple, precise and accurate HPTLC method for its estimation as bulk and in tablet dosage form. The chromatographic separation was carried out on precoated silica gel 60 F254 aluminium plates using mixture of chloroform:methanol (8:1...
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ژورنال
عنوان ژورنال: E-Journal of Chemistry
سال: 2011
ISSN: 0973-4945,2090-9810
DOI: 10.1155/2011/768014